Category Archives: Meso Facts

Mesothelioma is the name of a cancerous tumor that comes from the cells of the mesothelioum, a thin protective lining that covers many internal body organs including the lungs. Here you will find many facts about mesothelioma presented by Dr. Gill, a professor of Medicine and Pathology and head of the tumor and vascular biology laboratory at the University of Southern California. His clinical affiliation is with the USC Ambulatory Health Center and he is the Chairman of the Medical Advisory Board for the Mesothelioma Research Foundation of America.

PRESS RELEASES

Posted: May 2023

MesoRFA Newsletter: Spring 2023 Edition

  • Message from the Executive Director
  • 2nd Annual Tommy Engelhard Memorial Golf Out
  • California State Pipe Trades Aim to Cure Mesothelioma: Clay Shot at Birdslanding
  • Southern California Pipe Trades District Council 16 Golf Invitational
  • Heat & Frost Local 16 and Western Conference Roger Hamilton Memorial golf Tournament
  • Southern California Pipe Trades District Council 16 Aim to Cure Mesothelioma Clay Shoot
Posted: December 16, 2022

MesoRFA Newsletter: Spring 2022 Edition (May 2022)

  • Message from the Executive Director
  • California State Pipe Trades Aim to Cure Mesothelioma: Clay Shot at Birdslanding
  • Southern California Pipe Trades District Council 16 Golf Invitational
  • Heat & Frost Local 16 and Western Conference Roger Hamilton Memorial golf Tournament
  • Southern California Pipe Trades District Council 16 Aim to Cure Mesothelioma Clay Shoot
Event Date: October 3, 2022

District Council 16 Aim to Cure Mesothelioma at Moore N Moore

The Mesothelioma Research Foundation of America would like to congratulate and thank the Southern California Pipe Trades District Council 16 for organizing a fantastic event to help find a cure for mesothelioma. We returned to the Moore N Moore Sporting Clays Facility with a huge turnout, including UA International Representative Aaron Stockwell and Executive Director of the California State Pipe Trades, Mike Hartley, who joined us in generating an event record of over $55,000 for mesothelioma research! 100% of the money generated at the event will go directly to mesothelioma research to support clinical trials for better treatment options with the hope for an eventual cure.

You may recall that we lost a dear friend in 2021, former DC16 Business Manager Mike Layton, just a few weeks prior to last year’s event. Mike was the driving force behind bringing a clay shoot to Southern California and we are honored to hold the event in his memory. Our continued thoughts go out to the entire Layton Family and the Foundation would like to thank everyone who came out to spend the day remembering our friend and support such a great cause.

Mike Harley Aaron Stockwell-640px.jpg
  • Mike Harley Aaron Stockwell-640px.jpg
    Executive Director of the California State Pipe Trades, Mike Hartley and UA International Representative, Aaron Stockwell came to support our cause. Thank you, Mike and Aaron, for traveling to join us!
  • Mike Layton-640px.jpg
    Mike Layton was the driving force behind bringing this event to Southern California and we are honored to hold the event in his memory. Our continued thoughts go out to the entire Layton Family.
  • John Ferruccio-2022-640px.jpg
    DC16 Organizer, John Ferruccio and his team have done a fantastic job in planning and coordinating the Aim to Cure Mesothelioma clay shoot and other DC16 events. Thank you, John!
  • Dr Gill-640px.jpg
    Dr. Parkash Gill telling supporters how their donations are helping to develop new treatments, highlighting the combination of EphB-4 and Merk PD-1 antibody proving to be so successful that the FDA has designated it a breakthrough treatment!
  • Elizabeth and Jerry-2022-640px.jpg
    Foundation Executive Director, Elizabeth Ann Paul and CFO, Jerry Neil Paul thanking Southern California Pipe Trades DC16 for holding another great event and talking about the grass roots efforts of the Foundation.
  • 3rd-640px.jpg
    3rd Place
  • 2nd-640px.jpg
    2nd Place
  • 1st-640px.jpg
    1st Place
  • Top Shot-640px.jpg
    Top Shot !
  • Local 250 Crystal-640px.jpg
    Local 250 Crystal

After a great day on the course, supporters learned where their hard earned donations are going and how they are being used to fight this terrible disease. The Foundation’S Board Member and CFO, Jerry Neil Paul along with Executive Director Elizabeth Paul thanked DC and John Ferruccio for organizing another fantastic event and spoke about the roots of the Foundation. Dr. Parkash Gill then gave an update from the lab and highlighted the development of immunotherapy treatment EPhB-4 as a direct result of the donations and the hard work of so many. Dr. Gill then passed along the fantastic news that the combination of EphB-4 and Merk PD-1 antibody are proving to be so successful that the FDA has designated it a breakthrough treatment!

The Foundation would like to personally thank all of those who organized and supported this year’s events. Without the support and skills of people such as DC 16 Business Manager Rodney Cobos, DC 16 Assistant Business Manager Doug Marian and Director of Organizing John Ferruccio events like these would not be as successful as they are. Their leadership and their army of volunteers and supporters, make ALL of this possible and we THANK ALL OF YOU for your support and dedication!!!


Event Date: September 12, 2022

20th Annual Roger Hamilton Memorial Golf Invitational

On September 12, 2022, the 20th Annual Roger Hamilton Memorial Golf Invitational returned to the Napa Valley Country Club to generate funds for mesothelioma cancer research and clinical trials that will lead to better treatment options. We would like to thank each and every sponsor, golfer and volunteer who came out to help us generate approximately $100,000! As always, 100% of the funds generated will go toward supporting Dr. Parkash Gill’s research at the USC Norris Comprehensive Cancer Center.

Mike Patterson-2022-640px.jpg
  • Mike Patterson-2022-640px.jpg
    Local 5 Heat & Frost Insulator Business Manager, Mike Patterson, traveled from Los Angeles to join us. Roger Hamilton was a career Local 5 Insulator, making the event that more special for those who came to honor their brother.
  • Shane-2022-640px.jpg
    Foundation’s Assistant Executive Director, Shane Rucker heading out onto the course with the Foundation’s Founding Board Member and CFO, Jerry Neil Paul.
  • Billy and Daugther-640px.jpg
    Local 16 Heat & Frost Insulator President Billy Hodges volunteering his time with his daughter as they check supporters in to kick off their day. We thank everyone who gave up their day to volunteer, it means so much to us!
  • Chris Alan Mel-640px.jpg
    Local 16 Heat & Frost Insulator Business Manager, Chris Greaney, Local 16 Retirees President Alan Pierce and Event Chairman, Mel Breshears take time for a picture after a busy day. The Local 16 staff and volunteers who helped around the course are an amazing group of people to work with, thank you all!
  • Dr. Gill Speaking-2022-640px.jpg
    Dr. Parkash Gill expresses his gratitude towards supports, speaking on how their donations have helped to develop new treatments such as EphB-4. We are ecstatic with the results from the lab and the FDA designation of a breakthrough treatment!
  • EAP-2022-640px.jpg
    Foundation’s Executive Director, Elizabeth Ann Paul also volunteered her time on the course. Making the rounds to the volunteers and helping on the putting green. Thank you Elizabeth!
  • Fortino-2022-640px.jpg
    Local 16 Heat & Frost Insulator Business Agenet, Fortino Curiel serves as a Committee Member and helps with day of logistics such as the Hole in One Harley. Thank you Fortino!

You may recall that the event was established in 2002 by U.A. International Representative of the Pipetrades Jim Kellogg, and then California Building Trades President and Vice President, Bob Balgenorth, and Roger Hamilton. Roger was a former Business Manager of the Heat & Frost Insulators and it was Roger’s idea to support research into a cure for mesothelioma. Roger had been diagnosed with cancer several months before the first tournament and was determined to make the event a success. After Rogers passing, his wife Cindy Hamilton took over as Chairwoman and grew the event exponentially before the continued support of Doug Gamble and Mel Breshears of the Heat and Frost Insulators. Doug and Mel have planned and hosted the event over the last 5 years, and we cannot thank them enough for taking it upon themselves to ensure the continuation of the event and the honoring of Roger Hamilton’s memory.

To date, the Roger Hamilton Memorial Golf Invitational has raised approximately 1.8 million dollars for mesothelioma research! We owe our gratitude to the Western States Conference Heat and Frost Insulators, the Local 16 Heat and Frost Insulators, as well as all the building trades groups and vendors who continue to support the battle to defeat mesothelioma cancer. The success of the event is resulting in fantastic results in the lab at the USC Norris Comprehensive Cancer Center and is highlighted by Dr. Parkash Gill’s development of immunotherapy treatment EPhB-4. The combination of EphB-4 and PD-1 antibody are proving to be so successful that the FDA has designated it a breakthrough! The Foundation’s Executive Director, Elizabeth Paul and Dr. Gill were ecstatic to share this news with supporters and added that there several doctors affiliated with UC Davis, University of Chicago and others who are ready to offer the treatment to their patients suffering from this horrible disease.

Without the continual support from the staff and family of the Local 16 Heat and Frost Insulators, an event of this magnitude would not be possible. We thank Committee Chairman Mel Breshears, Co- Chair Chris Greaney, Chairman Emeritus Doug Gamble, Craig Rossi, Bill Hodges, Mark Plubell, Ben Espinoza, Fortino Curiel, China Soto, Geoff Millar, Alan Pierce, Jerry and Elizabeth Paul, and Shane Rucker. Without your efforts and energy this event would not have been possible. Your enduring support guarantees continued research and a cure will be found!


Event Date: July 11th 2022

District Council 16 Golf Invitational

The Mesothelioma Research Foundation of America would like to congratulate the Southern California Pipe Trades District Council 16 for organizing an amazing event! This year was special, marking the 19th Anniversary, and saw a full field of 144 golfers and supporters, joining at the Alta Vista Country Club. Together we generated over $145,000 for mesothelioma research! As always, 100% of the donations received will go directly toward research into clinical trials and treatment options for mesothelioma. Year after year, the organizers at District Council 16 have done an amazing job planning and promoting this event and we cannot thank them enough for their support and dedication. THANK YOU!

Parkash JNP 600w.jpg
  • Parkash JNP 600w.jpg
    Chairman of the Medical Advisory Committee, Dr. Parkash Gill with the Foundation’s CFO and Founding Board Member, Jerry Neil Paul before Dr. Gill passed along the fantastic news from the lab!
  • JNP 600w.jpg
    Foundation’s CFO and Founding Board Member, Jerry Neil Paul thanking everyone who continues to support the cause through donations and staying involved in the events held by DC16 and other trades groups. Thank you!
  • Vince Ferragamo 600w 10-2022.jpg
    Former LA Rams Quarterback, Vince Ferragamo raffled an autographed football and completed the pass to the winner. Thank you Vince, for coming out and supporting our cause.
  • John Ferruccio 600w 10-2022.jpg
    We cannot thank DC16 Director of Organizing, John Ferruccio enough for what he has accomplished. With his leadership, this event has grown hugely into what it is today. Thank you John!
  • Jaime Wyatt 600w.jpg
    Retired Assistant Executive Director of PIPE, Jaime Valdivia and the leadership of UA Local 398, Business Agent, David Hanson, Organizer, Wyatt Stiles and Business Manager, Bill Steiner played a phenomenal round and took home 1st place! Great round guys!
  • Hotel Group 600w.jpg
    Thank you to John Sanders and the CHM Hotel group for going above and beyond each and every year! Not only are they one of our largest donors but they also know their way around the green. Congrats on the 2nd Place!
  • John Doug Team 600w.jpg
    UA Local 250’s, Jon Munoz with DC16 and UA Local 78’s, Doug Wilson with Phill Fillers who are always helping hands at the events. Thank you Jon and Doug, and congrats on taking 3rd place!
  • Ducks Jersey 600w.jpg
    An autographed Anaheim Ducks jersey was raffled off and the winner couldn’t have been happier. Congrats Wade!

 

Participating in the event on behalf of the Foundation was Founding Board Member Jerry Neil Paul, Chairman of the Medical Advisory Committee. Dr. Parkash Gill, and Assistant Executive Director, Shane Rucker. After a great day of golf, Jerry spoke, thanking everyone for their support and highlighted the developments made at USC Norris Comprehensive Cancer Center. Dr. Parkash Gill, Chairman of the Foundation’s Medical Advisory Committee then spoke about the successes in the lab, with EphB-4 continuing to make progress in the FDA clinical trials process! We all hope to see the treatment become accessible and widely used by mesothelioma patients across the United States

The Foundation would like to personally thank Tournament Chairman and DC16 Director of Organizing John Ferruccio, Committee Member and DC 16 Business Manager Rodney Cobos, DC16’s Assistant Business Manager Doug Marian, Foundation Executive Director Elizabeth Ann Paul, Board Member Jerry Neil Paul, and Assistant Executive Director Shane Rucker for the great turnout. We would also like to thank Local 582’s Bob Modica who, for years, has brought his longtime friend Vince Ferragamo to the event to raffle an autographed football and make the most exciting pass of someone’s lifetime. We cannot be prouder of working with these great people. THANK YOU ALL FOR YOUR DEDICATION!!!


Event Date: June 3, 2022

2022 California State Pipe Trades Aim to Cure Mesothelioma Clayshoot

The June 2022 “Aim to Cure” event hosted by the California State Pipe Trades along with Foundation Board Member and Retired International Pipe Trades Representative Jim Kellogg was hugely successful in netting over $55,000 for mesothelioma research!

1st place 600w.jpg
  • 1st place 600w.jpg
    UA Local 342 Plumbers & Steamfitters joined us with multiple teams and took home the 1st Place trophy. Great shooting Ken Pastega, Steve Michich, Randy Lloyd and Bryan Jones!
  • 2nd place 600w.jpg
    Great shooting gentleman and congratulations on the 2nd Place!
  • 3rd place 600w.jpg
    Just a few clays separated 2nd and 3rd Place, fantastic shooting like usual from TNT Industrial Contractors!
  • Jim Mike JNP 600w.jpg
    Retired International Pipe Trades Representative, Jim Kellogg, speaking to supporters with the Executive Director of the California State Pipe Trades, Mike Hartley and the Foundation’s Founding Board Member, Jerry Neil Paul. We cannot thank them enough for their work in putting this great event on.
  • JNP Aaron 600w.jpg
    The Foundation’s Founding Board Member and CFO, Jerry Neil Paul with the current International Pipe Trades Representative, Aaron Stockwell. Thank you for the continued support, Aaron!
  • Top Shooter 600w.jpg
    Great shooting, we didn’t see you miss a clay all day long!
  • Duck N Cover 600w.jpg
    First time ever at a clay shooting event and you did great! Hope to see you back for 2023!

We had another beautiful day for this year’s Aim to Cure event, and a great turn out of participants to support this great cause, with 150 donors supporting the Aim to Cure Mesothelioma! We returned to the Birdslanding Hunting Preserve and Sporting Clay facility in Birdslanding, California which always provides a great venue for the event. Representing the Foundation were Board Members, Jim Kellogg and Jerry Neil Paul and Assistant Executive Director, Shane Rucker.

After making their way through the course, supporters and participants joined for lunch and the always popular raffle. Jim Kellogg kicked off the festivities by thanking everyone who come out year after year and have helped grow the event to what it is today. Jim then passed the mic to the Foundation’s Founding Board Member, Jerry Neil Paul, who talked about the advances being made by Dr. Parkash Gill at the USC Norris Comprehensive Cancer Center. The combination of immunotherapy treatment PD1 antibody with Dr. Gill’s treatment EphB-4 is proving to be an effective treatment. Our goal is to see this treatment option move through the FDA Clinical Trial process and become a widely used treatment option across the United States. With the support of participants in events such as “Aim to Cure” advances in mesothelioma treatment options will become a reality. California State Pipe Trades Executive Director Mike Hartley ended the day with the always popular raffle and thanked everyone for their continued support. We are all looking forward to 2023!

As always, 100% of the money raised during the “Aim to Cure” event will go towards mesothelioma cancer research. With these sizable donations we can all be assured that Dr. Gill’s research at USC / Norris Comprehensive Medical Center will move in the right direction. Thank you to all who participated and Jim Kellogg for putting together a fantastic event!


Event Date: May 20, 2022

Second Annual Tommy Engelhard Memorial Golf Outing

I wanted to share with you all an event that was held in memory of Mr. Tommy Engelhardt. Tom passed away at just 65 years old on April 18th, 2021, after a hard fought battle with Mesothelioma. Tom was just shy of retiring when he passed and left behind a wife, Cathy, 3 sons Thomas, Anthony and Andrew, and his sister Diane.

A decision was made to honor Tom’s memory and on May 20, 2022, the Second Annual Tommy Engelhard Memorial Golf Outing was held at Harbor Links Golf Course in Long Island, NY. The event saw 170 friends and family come together to celebrate Tom’s life. The overwhelming response to attend and share the tears, laughs and memories of Tommy led to the raising of over $11,450 in donations. The Mesothelioma Research Foundation of America is honored to have been chosen to put these donations towards making a difference!

 

As always 100% of the money donated to the Foundation will go directly towards the research into new treatment options for mesothelioma, something Tom’s friends and family were ecstatic to hear! The organizers of the event wanted to thank Elizabeth Paul, Shane Rucker and the Team at the Foundation for the support given to make the event successful.

The Foundation would like to thank Cathy Engelhardt, his brother in law, Nick Manchisi, and all of those who had a hand in putting on a great event and honoring their beloved Tommy.


Event Date: October 11, 2021

District Council 16 Aim to Cure Mesothelioma

The Mesothelioma Research Foundation of America would like to congratulate and thank the Southern California Pipe Trades District Council 16 for organizing a fantastic event to help find a cure for mesothelioma. This year’s DC16 Aim to Cure Mesothelioma event was held at the Moore N Moore Sporting Clays facility in San Fernando, CA and was successful in generating approximately $35,000 for mesothelioma research! Representing the Foundation was Founding Board Member Jerry Neil Paul and Assistant Executive Director Shane Rucker. As always, 100% of the money generated at the event will go directly to mesothelioma research to support clinical trials for better treatment options with the mission and hope for an eventual cure.

The event began with a somber tone, after the sad news that former DC16 Business Manager Mike Layton had passed away a few weeks prior. Mike was a fantastic person, a great friend to many of us at the Foundation and a driving force behind bringing the clayshoot to Southern California. John Ferruccio oversaw a moment of silence for our good friend, Mike, before we headed out on the course with him in all of our hearts. Our thoughts go out to the entire Layton Family.

Local 582 Pipefitters 600w.jpg
  • Local 582 Pipefitters 600w.jpg
    Thank you Local 582 for supporting the event. Great score guys!
  • Local 460 Will Estes 600w.jpg
    Local 460 Organizer Will Estes took home the Highest Score award with a great round on a course that proved to be tough. Well done Will!
  • Local 403 with Bob Jennings and Sid Stolper 600w.jpg
    Walt French and his team from UA Local 403 with the Northern California Regional Director for the CA State Building Trades, Bob Jennings, and United Association District 5 Vice President, Sid Stolper. It was great seeing all of you again!
  • JNP Speaking 600w 2021-10-11.jpg
    The Foundaiton’s Chief Financial Officer and Founding Board Member, Jerry Neil Paul, thanks all of the supporters and gives an update from the Lab at USC Norris Comprehensive Cancer Center.
  • Local 460 Javier Flores 600w.jpg
    Local 460 Business Agent, Javier Flores took home the grand prize! Congratulations and thank you, Local 460 for coming out and supporting the event!

We had some noteworthy guests who joined us in support of the Foundation and DC 16’s mission. UA Administrative Assistant to the General President, Derrick Kualapai, UA Local 342 Business Manager, Che Timmons, UA International Representative for California and Hawaii Aaron Stockwell and UA Vice President of District 5 Sid Stolper, who was instrumental in the growth of the DC16 events when he served as Business Manager.

After a beautiful day in the Angeles National Forest, the event’s supporters gathered for a great BBQ lunch and the always popular raffle. Before giving away some amazing prizes, sponsors and supporters learned where their hard earned money was going and how it was being used to fight this terrible disease. Speaking at the event on behalf of the Foundation was Board Member and CFO, Jerry Neil Paul. After thanking John Ferruccio for organizing another fantastic event, as well as everyone in attendance, Jerry spoke about the roots of the Foundation and the massive efforts taken in developing new drugs for the treatment of mesothelioma. He then passed along the news from Dr. Gill’s Lab at USC Norris Comprehensive Cancer Medical Center that the immunotherapy treatments EphB-4 and PD-1 were submitted to the FDA Clinical Trials process with collaboration with doctors affiliated with facilities such as UC Davis and University of Chicago.

The Foundation would like to personally thank all of those who organized and supported this year’s events. Without the support and organizing skills of people such as DC 16 Business Manager Rodney Cobos, DC 16 Director of Organizing John Ferruccio and all of the support from DC16. Without the team of volunteers and supporters, these types of events would not be possible. THANK YOU ALL FOR YOUR SUPPORT AND DEDICATION!!!


Event Date: September 20, 2021

Roger Hamilton Memorial Golf Invitational

On September 20, 2021, the Roger Hamilton Memorial Golf Invitational returned for its 19th presentation at the Napa Valley Country Club, to raise funds for mesothelioma cancer research and further the development of new treatment options. This year’s event saw a full field of golfers, who came together to raise over $91,000! As always, 100% of the funds generated will go toward supporting Dr. Parkash Gill’s research at the USC Norris Comprehensive Cancer Center.

The Roger Hamilton Event would not be possible without the continued support of Doug Gamble, Secretary Treasurer of the International Assoc. of Heat & Frost Insulators, Mel Breshears Vice President of the Western States Conference International and Chris Greaney, Business Manager of the International Association of Heat and Frost Insulators Local 16. We thank them all, as they have taken it upon themselves to ensure the continuation of the event and honoring Roger Hamilton’s memory. To date, the Roger Hamilton Memorial Golf Invitational has raised approximately 2 million dollars for mesothelioma research! We also owe our gratitude to Cindy Hamilton and the Hamilton family, along with all of the building trades, contractors and vendors who continue to support the battle to defeat mesothelioma cancer.

Aaron Doug Mel 600w.jpg
  • Aaron Doug Mel 600w.jpg
    Newly appointed International Pipetrades Representative Aaron Stockwell with Hamilton Golf Committee Chairmen, Doug Gamble and Mel Breshears. Congratulations on the new position Aaron!
  • Doug Chris 600w.jpg
    Doug Gamle, the General Secretary-Treasurer of the International Association of Heat & Frost Insulators, presents the Heat and Frost Insulators Local 16, Business Manager, Chris Greaney, with a token of gratitude for the continued support in planning the Roger Hamilton Memorial Golf Invitational. Chris and Local 16 Staff are instrumental in the planning and providing the day of support for the event. We cannot thank them all enough!
  • Doug Jerry Mel 600w.jpg
    The Foundation’s CFO, Jerry Neil Paul (center) with Doug Gamble and Mel Breshears. We cannot thank Doug and Mel enough for their continued efforts in the success of the Roger Hamilton Memorial Golf Invitational Tournament.
  • Mel 600w.jpg
    Vice President of the Western States Conference of Heat and Frost Insulators, Mel Breshears has worked tirelessly to ensure the Hamilton Event is a continued success and an event that everyone looks forward to every year. Thank you Mel, for your hard work and dedication to this cause.
  • Local 5 600w.jpg
    Local 5 Heat & Frost Insulators Business Manager Mike Patterson and his team traveled from Los Angeles to Northern California for the event. Thank you Mike and team, for coming up to support the Foundation and enjoying the day with us.
  • Shane Jerry 600w.jpg
    The Foundation’s Assistant Executive Director, Shane Rucker and CFO Jerry Neil Paul share important news from Dr. Parkash Gill and the Lab at the USC Norris. We are all very excited to hear that the immunotherapy treatments, EphB-4 and PD-1, have been submitted to the FDA Clinical Trials process.
  • Volunteer1 600w.jpg
    Thank you to all of the Volunteers from Local 16 and the Foundation who had a hand in planning the event as well as those who volunteered their time to offer their assistance at the event. Thank you!
  • Volunteers 2 600w.jpg
    Local 5 Heat & Frost Insulators Retirees President Alan Pierce flanked by Doug Gamble and Mel Breshears as they present him with a bottle of wine as a thank you for volunteering at the event. Thank you for the hard work and great pictures, Alan!

 

After a great day on the course, we joined in the clubhouse for drinks, dinner, and catch up with friends. Doug Gamble and Mel Breshears thanked the sponsors who come out year after year, and the volunteers for their roles in making the event run smoothly and successfully. Jerry Neil Paul, one of the Foundation’s founding board members and CFO gave a short history of the event and how much it means to us that the event is as strong as ever after 19 years. Shane Rucker, Assistant Executive Director of the Foundation then provided an update from Dr. Gill, USC Senior Professor, Board Certified Oncologist, Hematologist and head of various FDA approved clinical trials. Dr. Gill is also Chairman of the Medical Advisory Committee of the Mesothelioma Research Foundation of America. Dr. Gill, in his Clinical Trials, has shown the ability to identify mutated cancer genes and the development of treatment options that can target and kill cancer cells. There has been great progress thanks to the success of the Hamilton event. It can also be seen in the development of immunotherapy treatments EphB-4 and PD-1 and their submission to the FDA Clinical Trials process and collaboration with doctors affiliated with facilities such as UC Davis and University of Chicago.

Such a great event takes too many people to thank, but certain individuals play a pivotal role in ensuring its success. To Committee Chairman Doug Gamble, Co-Chair Mel Breshears, Chris Greaney, Mike Patterson, Stan Danielson, Bill Hodges, Mark Plubell, Ben Espinoza, Fortino Curiel, China Soto, Geoff Millar, Alan Pierce, Jerry and Elizabeth Paul, and Shane Rucker: we wish to express our greatest appreciation. Without your efforts and energy this event would not have been possible. Your enduring support guarantees continued research into mesothelioma. With sustained effort, a cure will hopefully be found!


Event Date: August 6, 2021

Heat & Frost Insulators Local 16 Retirees Luncheon

On August 6th, the Heat & Frost Insulators Local 16 retirees group held their first luncheon since the COVID pandemic began in March of 2020. The Foundation’s Founding Board Member, Jerry Neil Paul, was in attendance and eager to give everyone an update as to what has been happening at the Foundation.

Jerry Paul opened by reporting on the success of the first two events held in 2021 and the planning of the Roger Hamilton Golf Invitational scheduled for September 20, 2021. He then passed along the great news from Dr. Parkash Gill’s lab at USC, which continues to successfully treat mesothelioma patients with the combination of immunotherapy drug PD-1 with EphB-4. Jerry highlighted that the treatment has been so affective that it has been submitted to the FDA for Phase 2 clinical trials!

JNP-Mel-Alan-Geoff 600w.jpg
  • JNP-Mel-Alan-Geoff 600w.jpg
    Founding Boardmember Jerry Paul with Vice President of the Western States Conference International, Mel Breshears, Local 16 Retirees Club President Alan Pierce and Retired Insulator and Hamilton Event Committee Member, Geoff Millar.
  • Chris-JNP-Yvonne 600w.jpg
    The Foundation’s CFO, Jerry Paul, accepts a donation from Yvonne Lasserre of the Operating Engineers Credit Union and Local 16 Business Manager Chris Greaney. Thank you, OE Credit Union!
  • Bill-Chris 600w.jpg
    Heat & Frost Insulators Local 16 President Bill Hodges with Local 16 Business Manager Chris Greaney. We cannot thank the staff and leadership at Local 16 enough for their continued partnership and support in hosting the Roger Hamilton Memorial Golf Invitational!

Following his update, Jerry Paul accepted a check on behalf of the Foundation that was presented by Yvonne Lasserre of the Operating Engineers Credit Union from their points program. We cannot thank enough the Operating Engineers and the leadership at Local 16, including Business Manager Chris Greaney, President Bill Hodges and Vice President of the Western States Conference International, Mel Breshears, for their continued support!


Event Date: July 12, 2021

Southern California Pipetrades District Council 16 Annual Golf Invitational

Everyone at the Mesothelioma Research Foundation of America would like to congratulate the Southern California Pipe Trades District Council 16 for organizing an amazing event! We saw a huge turnout for the 18th Annual Golf Invitational at the Alta Vista Country Club, with over 150 golfers, including the return of former LA Rams legendary quarterback, Vince Ferragamo. Vince has become a regular at the event, who was invited by his very good friend and retired UA Local 582 Business Agent, Bob Modica. Together we generated over $140,000 for mesothelioma research, 100% of which will go directly toward research into clinical trials and better treatment options for mesothelioma with the hope of an eventual cure. The leadership of District Council 16, including Tournament Director and Director of Organizing John Ferruccio, Committee Member and Business Manager Rodney Cobos, and Assistant Business Manager, Doug Marian, goes above and beyond in planning an event that everyone looks forward to. We cannot thank them enough for the years of support and dedication. THANK YOU!

John Ferruccio 600w.jpg
  • John Ferruccio 600w.jpg
    Dhttps://mesorfa.orgistrict Council 16 Director of Organizing and Tournament Director, John Ferruccio, continues to do an amazing job of promoting and building this event. Thank you John and everyone at DC16 for your continued friendship and dedication to the cause!
  • UA Team 1 600w.jpg
    District Council 16 Assitant Business Manager Doug Marian, UA International Pipe Trades Representative Derrick Kualapai, District Council 16 Business Manager Rodney Cobos and UA Local 484 Business Manager Shane Boston. The Foundation is grateful for your support!
  • JNP Speaking 600w.jpg
    The Foundation’s Founding Boardmember Jerry Neil Paul, thanks everyone who comes together to support this great event and continue to go above and beyond in raising awareness.
  • Dr GIll Speaking 600w.jpg
    The Foundation’s Chairman of the Medical Advisory, Dr. Pakash Gill, gives an update on the new treatment option of PD-1 and EphB-4 being submitted to the FDA for Phase 2 clinical trials!
  • Dr Gill-John 600w.jpg
    Tournament Director, John Ferruccio, thanks Dr. Gill for coming out to speak at the event and the great work he is doing at the USC Norris Comprehensive Cancer Center in developing new treatment options for this horrible disease.
  • Vince Ferragamo 600w.jpg
    Former Los Angeles Rams quarterback Vince Ferragamo auctions off an autographed football and goes for the pass!
  • Parkash-Jaime 600w.jpg
    Dr. Parkash Gill and PIPE Assistant Executive Director Jaime Valdivia share a laugh before dinner. Jaime has been a longtime supporter, friend and always dressed to impress!
  • CHM 600 h.jpg
    John Sanders and the CHM Hotel Group have consistently been one of the event’s top sponsors and put together a couple of teams of great golfers! Thank you, John, and all of the folks at CHM who came out and had fun with us!
  • Shane-Local 5 600w.jpg
    Assistant Executive Director Shane Rucker tees off on the hole sponsored by Heat and Frost Insulators Local 5 hole. Thank you for your sponsorship, Local 5!
  • JNP Shane Tee Off 600w.jpg
    Founding Boardmember Jerry Neil Paul and Assistant Executive Director Shane Rucker tee off with District Council 16 and the Paul Law Firm.
  • Eddie-Barnes 600w.jpg
    Long time friend and supporter, Eddie Barnes, of UA Local 250, traveled from Idaho to participate. Thank you for coming out Eddie!

Participating in the event on behalf of the Foundation was, Board Member Jerry Neil Paul, Chairman of the Medical Advisory Committee, Dr. Parkash Gill, and Assistant Executive Director, Shane Rucker. After a great day of golf, Jerry gave a heartfelt thank you to everyone for supporting the event year after year, and highlighting the new treatment options coming from the lab at USC Norris Comprehensive Cancer Center. Dr. Parkash Gill, Chairman of the Foundation’s Medical Advisory Committee then reported the great news that USC continues to successfully treat mesothelioma patients with the combination of immunotherapy drug PD-1 in combination with EphB-4! Dr. Gill added that there have been several recent research collaborations in addition to the treatment being submitted to the FDA for Phase 2 clinical trials!

The Foundation would like to personally thank all of you who support and turn out for this great event. With the participation from UA International Pipe Trades Representative, Derrick Kualapai and California Pipe Trades Executive Director, Aaron Stockwell, and the organizing skills of people such as DC16’s John Ferruccio, Rodney Cobos, Doug Marian, Foundation Executive Director Elizabeth Ann Paul, Board Member Jerry Neil Paul and Assistant Executive Director, Shane Rucker, this event and great turnout would not be possible. They have all done a fantastic job, year in and year out, and we cannot be more proud of working with these great people. THANK YOU


Event Date: June 4, 2021

Califonia State Pipe Trades’ Aim To Cure – Birdslanding, California

June 4, 2021, marked the 15th annual California State Pipe Trades’ Aim to Cure Mesothelioma sporting clay shoot event hosted by Jim Kellogg, retired U.A. Pipe Trades International Representative and former California State Fish and Game Commissioner, and Aaron Stockwell, the California State Pipetrades Executive Director. Sponsors and the supporters of the Mesothelioma Research Foundation of America converged on the Birds Landing Hunting Preserve and Sporting Clay facility just outside of Concord, California. The event was a huge success, with over 180 shooters participating, helping to raise over $75,000 for mesothelioma research! The fantastic support and turnout ensures the continued development of new and viable treatment options for mesothelioma. The Foundation was represented by Jerry Neil Paul and Jim Kellogg, both Board Members and Assistant Executive Director Shane Rucker.

JNP Jim 600W.jpg
  • JNP Jim 600W.jpg
    Foundation Boardmembers Jerry Neil Paul and Jim Kellogg kick off the event, thanking everyone for the HUGE turnout of over 180 shooters!
  • JNP1 600w px.jpg
    Foundation Boardmember, Jerry Neil Paul Paul passes along the fantastic news from Dr. Parkash Gill that his immunotherapy treatment of EphB-4 and PD-1 had been introduced to the FDA for Phase 2 Clinical Trials!
  • JNP Geoff Shane 600w px.jpg
    Foundation Boardmember Jerry Neil Paul and Assistant Executive Director Shane Rucker with retired Local 16 insulator Geoff Millar.
  • Jim Speaking 600w px.jpg
    Foundation Boardmember, retired U.A. Pipe Trades International Representative and former California State Fish and Game Commissioner, Jim Kellogg thanks supporters for making this year one of the most successful clay shoots we have held. Thank you Jim!
  • Aaron Speaking 2 600w px.jpg
    California Pipe Trades Executive Director, Aaron Stockwell takes the mic to run the always popular raffle. We cannot thank Aaron and his staff enough for hosting the event and making a difference in the fight against this terrible disease.
  • Mikich Kualapai JNP Timmons 600w px.jpg
    UA International Special Representative, Mike Mikich, UA International Representative, Derrick Kualapai, Foundation Boardmember Jerry Neil Paul and UA Local 342 Business Manager, Che Timmons. UA Local 342 came out in massive support of the event! We cannot thank them enough!
  • Mel JNP Alan 600w px.jpg
    Vice President of the Western States Conference International Insulators, Mel Breshears with Jerry Neil Paul and the Local 16 Insulators Retirees President, Alan Pierce.
  • Shane Partch 600w px.jpg
    Foundation Assistant Executive Director, Shane Rucker with Retired CA State Pipe Trades Executive Director, Greg Partch.
  • UA Local 403 Team 600w px.jpg
    Retired Business Manager, Walt French and current Business Manager David Baldwin, brought their team from UA Local 403 in San Luis Obispo to support the cause. Thank you Mike, Walt, and David for making it up to Birds Landing!
  • Top Shot-Mitchell 600w px.jpg
    Mark Mitchell took this year’s Top Shot award. Mark has been a long-time supporter of the Foundation following a friend’s passing from mesothelioma. Thank you for the support Mark!
  • 1st Place- TNT Industrial 600w px.jpg
    The 1st Place team from TNT Industrial Contractors are regulars at this event and always bring their A-game.
  • Jim-Derrick 600w px.jpg
    Foundation Boardmember, retired U.A. Pipe Trades International Representative and former California State Fish and Game Commissioner, Jim Kellogg with UA International Representative, Derrick Kualapai.

After the shoot had concluded, Jim Kellogg thanked attendees, expressing his gratitude for the huge support after a year of uncertainty. Next, Jerry Paul spoke of the importance of staying involved in the fight to raise awareness, highlighting the fantastic development from Dr. Parkash Gill. Shortly before the event, Dr. Gill passed along the wonderful news that his treatment, a combination of immunotherapies EphB-4 and PD-1, had been introduced to the FDA for Phase 2 Clinical Trials! This is a huge milestone. The treatment is currently being administered to mesothelioma patients with support from the USC Norris Comprehensive Cancer Center and in collaboration with UCLA and UC Davis. Jerry Paul then passed the mic to Aaron Stockwell to say a few words before raffling off a few items to support the cause.

As always, 100% of the funds raised at the Birdslanding event will go directly towards mesothelioma cancer research at Dr. Parkash Gill’s lab at USC Norris Comprehensive Medical Center. With these sizable donations, we can be assured that Dr. Gill’s mesothelioma cancer research at USC/ Norris Comprehensive Medical Center will be moving in the right direction with the goal of expanding the clinical trials to other interested universities. Thank you to all who participated and made the event a success!

District Council 16 Cure Meso Clayshoot

October 14, 2019

The Mesothelioma Research Foundation of America would like to thank everyone who attended this year’s Cure Meso Clayshoot and those at the Southern California Pipetrades District Council 16 who make this event possible year after year. We returned to the Moore ‘N Moore Sporting Clays facility in San Fernando Valley, CA. We saw a large turnout of shooters who joined to raise over $50,000 for mesothelioma research! Attending the event on behalf of the Foundation were Executive Director Elizabeth Ann Paul, Founding Board Members Jim Kellogg and Attorney Jerry Neil Paul, Chairman of the Medical Advisory Committee, Dr. Parkash Gill and Assistant Executive Director, Shane Rucker. As always, 100% of the money generated at the event will go directly to mesothelioma research to help find a cure for this terrible disease.

The Foundation’s Assistant Executive Director, Shane Rucker, Executive Director, Elizabeth Ann Paul, Chairman of the Medical Advisory Committee, Dr. Parkash Gill and Founding Board Member and Attorney, Jerry Neil Paul would like to thank everyone who participates and volunteers their time at the events to further the research and development of new mesothelioma treatments.

The Mesothelioma Research Foundation of America would like to thank everyone who attended this year’s Cure Meso Clayshoot and those at the Southern California Pipetrades District Council 16 who make this event possible year after year. We returned to the Moore ‘N Moore Sporting Clays facility in San Fernando Valley, CA. We saw a large turnout of shooters who joined to raise over $50,000 for mesothelioma research! Attending the event on behalf of the Foundation were Executive Director Elizabeth Ann Paul, Founding Board Members Jim Kellogg and Attorney Jerry Neil Paul, Chairman of the Medical Advisory Committee, Dr. Parkash Gill and Assistant Executive Director, Shane Rucker. As always, 100% of the money generated at the event will go directly to mesothelioma research to help find a cure for this terrible disease.

Southern California Pipetrades District Council 16 Director of Organizing, John Ferruccio has worked tirelessly to ensure the success of the events. It is an absolute pleasure to work with John and his team at DC16 and we cannot thank him enough!

Shooters were blessed with beautiful Southern California weather as we took our best shots at the sporting clays flying over the picturesque canyons of the Angeles National Forest. Sponsors and supporters then gathered for a delicious BBQ and to learn how their donations are helping in the fight against his horrible disease. District Council 16 Director of Organizing John Ferruccio thanked everyone who came out to support the event and those who volunteer their time at MESORFA.

Foundation’s Founding Board Member and Attorney, Jerry Neil Paul thanks everyone in attendance and everyone at the Southern California Pipetrades District Council 16 who had a hand in making the Aim to Cure Mesothelioma event such a success!

Speaking on behalf of the Foundation were Jerry and Elizabeth Paul who first thanked everyone in attendance and those who had a hand in making the event such a success. Elizabeth Paul talked about the humble roots of the Foundation and how proud we are to see the new developments coming from the lab. Dr. Parkash Gill then spoke about the progress being made by his team of doctors at USC Norris Cancer Center and the promising results of PD-1 and EphB-4 treatment and its expansion into additional treatment facilities across the United States as UC Davis and UCLA.

Southern California Pipetrades District Council 16 Director of Organizing, John Ferruccio and Chairman of the Medical Advisory Committee, Dr. Parkash Gill speak together at the 2019 Aim to Cure Mesothelioma Clayshoot hosted by the Southern California Pipetrades District Council 16.

The Foundation would like to personally thank all of those who organized and supported this year’s Aim to Cure Meso Clayshoot. Without the support and organizing skills of people such as DC 16 Business Manager Rodney Cobos, DC 16 Director of Organizing John Ferruccio and International Piptrades Representative Jim Kellogg these types of events would not be possible.

THANK YOU ALL FOR YOUR SUPPORT AND DEDICATION!!!

Southern California Pipetrades District Council 16 Annual Golf Invitational

July 8, 2019

This year’s Southern California Pipetrades District Council 16 Annual Golf Invitational was held at the beautiful Alta Vista Country Club in Placentia, CA and marks the event’s 17th anniversary. Over 144 golfers attended the event to support finding a cure for mesothelioma, helping to generate over $140,000 for mesothelioma cancer research!

Former LA Rams Quarterback, Vince Ferragamo and District Council 16 Director of Organizing, John Ferruccio help push the event’s donation total higher than ever before with the auction of an autographed football.

Representing the Mesothelioma Research Foundation of America were Founding Board Member and Attorney Jerry Neil Paul, Executive Director Elizabeth Ann Paul, Chairman of the Medical Advisory Committee Dr. Parkash Gill and Assistant Executive Director Shane Rucker.

After a great day out on the course, golfers and supporters joined for a bite to eat and to learn how their donations are helping to fund better treatment options for mesothelioma and an eventual cure. The evening was kicked off by DC16 Director of Organizing John Ferruccio. John over the last decade has been the MC, Master of Ceremonies extraordinaire. John then introduced speakers Jerry and Elizabeth Paul.

Founding Board Member and Attorney, Jerry Neil Paul thanks everyone who volunteers their time to ensure that 100% of every dollar donated can go directly to Dr. Gill’s research at the Mesothelioma Research Lab at USC/Norris Comprehensive Cancer Center.

Jerry Paul thanked everyone in attendance and expressed how grateful the Foundation is for being associated with such a supportive group of people. Elizabeth Paul then spoke on the importance of the fundraisers in funding research and the development of more effective treatment options.

The Foundation’s Executive Director, Elizabeth Ann Paul informs participants how important their donations are in helping in the research and development of new treatment options for mesothelioma.

Elizabeth expressed how we are all volunteers, with the Paul Law Firm paying 100% of the administrative costs so 100% of donations can go to Dr. Gills research and clinical treatment development. Dr. Parkash Gill then spoke about the research and development of new medicines by the Mesothelioma Research Lab at USC/Norris Comprehensive Cancer Center. Dr. Gill highlighted the promising results of the PD-1 and EphB-4 treatment and its expansion into additional treatment facilities across the United States as UC Davis and UCLA.

Former LA Rams Quarterback, Vince Ferragamo tosses an autographed football to a generous donor at the 2019 DC16 Golf Invitational befitting The Mesothelioma Research Foundation of America.

The Foundation would like to personally thank all of those who sponsored, supported and attended the event. Without your support and the organizing skills of people such as Rodney Cobos, Mike Layton, John Ferruccio, Doug Wilson, DC 16 Staff and Committee members Jerry and Elizabeth Paul, this event and great turnout would not have been possible.

THANK YOU ALL FOR YOUR DEDICATION!!!

Roger Hamilton Memorial Golf Invitational

On June 24, 2019, the Roger Hamilton Memorial Golf Invitational was hosted by the Insulators International Vice President, Doug Gamble and Heat and Frost Insulators Local 16 Business Manager, Mel Breshears at the pristine Napa Valley Country Club. We witnessed a great turnout with a full field of golfers joining sponsors and volunteers to generate awareness, and raise over $83,000! 100% of the donations will go toward supporting Dr. Parkash Gill’s research and clinical trials within the USC Norris Comprehensive Cancer Center for new and viable treatment options for mesothelioma patients.

Insulators International Vice President, Doug Gamble and Heat and Frost Insulators Local 16 Business Manager, Mel Breshears are the Events’ Hosts and MCs. Doug and Mel have gone above and beyond in their leadership and we cannot thank them enough!

This event would not have been possible without the leadership of, Doug Gamble and Mel Breshears and all of the people working behind the scenes at Heat & Frost Insulators Local 16. You may recall that 3 years ago the Insulators took it upon themselves to ensure not only the continuation of the event, but the honoring of Roger Hamilton’s memory through fund raising and awareness efforts. For their dedication and continued success, we owe our gratitude to the Western States Conference Heat and Frost Insulators, the Local 16 Heat and Frost Insulators, as well as all of the building trades groups who come out and participate year after year.

After a great round of golf, the supporters reconvened in the clubhouse for dinner, and to learn where and how their donations were being used. Doug and Mel kicked off the festivities, thanking both the sponsors and the event’s volunteers for making the event possible.

Foundation’s Executive Director, Elizabeth Ann Paul with Hamilton Event Volunteers. THANK YOU to each and every one of the volunteers for giving their time and helping to make the event fun but also an enormous success!

Elizabeth Ann Paul, the Mesothelioma Research Foundation of America’s Executive Director, informed the sponsors of the Foundation’s history, pointing out its critical help in the development of better treatment options for mesothelioma.

Chairman of the Medical Advisory Committee, Dr. Parkash Gill gives a progress report on the promising results of the PD-1 and EphB-4 treatment option and its expansion into additional treatment facilities across the United States.

Dr. Parkash Gill, Chairman of the Medical Advisory Committee, then gave a progress report on the promising results of the PD-1 and EphB-4 treatment option and its expansion into additional treatment facilities across the United States, including UC Davis.

Local 16 Insulators Retirees President and Hamilton Event Volunteer Alan Pierce, Foundation Assistant Executive Director, Shane Rucker, Committee Member Geoff Millar and Board Member Jerry Neil Paul pose for a picture as they greet golfers registering for the event.

We cannot be more proud of the results we are seeing in the lab and the continued success of the Hamilton event. Committee Chairman Doug Gamble and Co-Chair Mel Breshears, thanked Committee Members Stan Danielson, Bill Hodges, Mark Plubell, Ben Espinoza, Chris Greaney, Fortino Curiel, Geoff Millar, Jerry and Elizabeth Paul, Shane Rucker and their volunteers, sponsors and the building trades who supported this event. Without their energy and leadership we would not see these amazing results.

THANK YOU ALL who have a hand in making this possible

Founding Board Member and Attorney Jerry Neil Paul and Hamilton Golf Committee Member, Geoff Millar pose outside the Napa Valley Country Club clubhouse as they greet sponsors of the event.
Founding Board Member and Attorney Jerry Neil Paul, International Pipetrades Representative, Derrick Kualapai and Paul Law Firm Trial Attorney, Joshua S. Paul working together to raise awareness at the 2019 Roger Hamilton Memorial Golf Invitational.

California Pipetrades Aim to Cure – Birdslanding, California

June 7, 2019

The 2019 “California Pipetrades Aim to Cure” mesothelioma clayshoot, hosted by Foundation Board Member and Retired International Pipetrades Representative, Jim Kellogg, kicked off a great year of fundraising, netting approximately $60,000 for mesothelioma research! We witnessed a huge turnout of over 170 shooters and supporters at the Birdslanding Hunting Preserve and Sporting Clay Facility. Representing the Foundation at the event were Board Member’s Jim Kellogg and attorney Jerry Neil Paul, as well as Assistant Executive Director Shane Rucker.

Foundation Board Member, Retired International Pipetrades Representative and event host, Jim Kellogg with Board Member and Attorney Jerry Neil Paul, speaking to supporters on the importance of staying involved.

After everyone had taken their best shot at the sporting clays, Birdslanding provide a delicious tri-tip lunch before Jim Kellogg thanked everyone who attended and highlighted how important it is to stay involved. Jerry Neil Paul was then introduced, who thanked Jim Kellogg and the Executive Director of the California State Pipetrades, Gregg Partch, for organizing and hosting such a great event year after year. Jerry then informed the supporters of how the proceeds of the event would go towards the continued research and development of new mesothelioma treatment options. He also noted the fantastic news of the discussions between Dr. Parkash Gill and other University cancer treatment facilities in working together to expand the use of treatment of PD-1 and EphB-4 along with USC Norris Comprehensive Cancer Center. The mic was handed over to Trial Attorney Joshua Paul for the always popular raffle and his masterful and comical performance generated laughs and more donations for the Foundation!

Heat and Frost Insulators Local 16 Business Manager, Mel Breshears with the Foundation’s founding Board Member, Jerry Neil Paul before heading out to participate in the 2019 California State Pipetrades Aim to Cure Mesothelioma Clayshoot.

With the Foundation’s administrative costs underwritten by the Paul Law Firm, 100% of the event’s net proceeds will go towards mesothelioma cancer research. With these sizable donations we can be assured that Dr. Gill’s research and clinical trials for better treatment options continue moving in the right direction.

We want to wish Gregg a very happy retirement and look forward to continuing our work with newly promoted Executive Director of the California State Pipetrades Council, Mike Layton. Mike is a longtime friend of the Foundation, serving as the Southern California Pipetrades District Council 16 for the last 10 years and hosting many of the Foundation’s events. Thank you to all who participated and make our events possible!

Roger Hamilton Memorial Golf Invitational

June 25, 2018

Mesothelioma Research Foundation of America MesoRFA.org
Heat & frost Insulators Local 16 Business Manager Mel Brashears and the Foundation’s very own Elizabeth and Jerry Neil Paul prepare for the day’s festivities.

On June 25, 2018, the Roger Hamilton Memorial Golf Invitational returned for its 16th presentation to the Napa Valley Country Club generating funds for mesothelioma cancer research and clinical trials that will lead to better treatment options. This year’s event saw a turnout of 140 golfers and generated approximately $65,000! As always, 100% of the funds generated will go toward supporting Dr. Parkash Gill’s research at the USC Norris Comprehensive Cancer Center.

Mesothelioma Research Foundation of America MesoRFA.org
Local 16 Business Manager Mel Brashears and International Vice President Doug Gamble(center). We cannot thank you and your team at Local 16 for putting on a great event and supporting this great cause.

The Roger Hamilton Event would not be possible without the continued support of Doug Gamble and Mel Breshears of the Heat and Frost Insulators. For the third year, Gamble, the International Vice President, and Breshears, the Business Manager of Local 16, have planned and hosted the event. We thank them both as they have taken it upon themselves to ensure the continuation of the event and the honoring of Roger Hamilton’s memory. To date, the Roger Hamilton Memorial Golf Invitational has raised approximately 1.7 million dollars for mesothelioma research! For the continued success, we owe our gratitude to the Western States Conference Heat and Frost Insulators, the Local 16 Heat and Frost Insulators, as well as all of the building trades groups and vendors who continue to support the battle to defeat mesothelioma cancer.

Mesothelioma Research Foundation of America MesoRFA.org
Chairman of the Foundation’s Medical Advisory Committee, Dr. Parkash Gill, speaks to guests highlighting the great promise EPh-B4 and PD-1 have shown in studies.

After a great round of golf, supporters reconvened in the clubhouse for drinks, dinner, and learn how their donations are being used. Doug Gamble and Mel Breshears were the first to speak, thanking both the sponsors for their support and the volunteers for their roles in making the event a success. Elizabeth Paul, Executive Director of the Foundation informed the sponsors about the history of the Foundation, pointing out its critical help in the development of better treatment options for mesothelioma. Dr. Parkash Gill, Chairman of the Foundation’s Medical Advisory Committee then highlighted the use of immunotherapy treatment PD-1 antibody in combination with EphB-4 and the successes shown in the laboratory. Dr. Gill added that there have been several recent research publications in collaboration with doctors affiliated with UC Davis and University of Chicago regarding EphB-4! To close, the two acknowledged the continual support from the staff and family of the Local 16 Heat and Frost Insulators, and for their role in assuming the direction of the event.

Mesothelioma Research Foundation of America MesoRFA.org
Jerry Neil Paul and Local 16’s Mark Plubell having fun together before a great round on the course.

An event of this magnitude takes too many people to thank, but certain individuals played a pivotal role in ensuring its success. To Committee Chairman Doug Gamble, Co-Chair Mel Breshears, Stan Danielson, Bill Hodges, Mark Plubell, Ben Espinoza, Chris Greaney, Fortino Curiel, China Soto, Geoff Millar, Alan Pierce, Jerry and Elizabeth Paul, and Shane Rucker: we wish to express our greatest appreciation. Without your efforts and energy this event would not have been possible. Your enduring support guarantees continued research into mesothelioma. With sustained effort, a cure will hopefully be found!

Mesothelioma Research Foundation of America MesoRFA.org
The Foundation’s Executive Director, Elizabeth Ann Paul, Founding Board Members, Jerry Neil Paul and Jim Kellogg, and Assistant Executive Director, Shane Rucker represent the Foundation at the Roger Hamilton Memorial Golf Tournament.

Study Shows Asbestos Bans are Slow to Reduce Malignant Mesothelioma Rates

It has been more than 32 years since Denmark began in 1972 a ban on the use of asbestos insulation. In the late 1980s, Denmark also extended its ban to include other products containing asbestos.  And now, Denmark is one of 55 countries who have completely banned asbestos  products.  

But according to the new study of mesothelioma in Denmark, a steady rise in cases of this asbestos-linked cancer that began in the 1950s is still going on.

Mesothelioma and Asbestos

Mesothelioma is an aggressive cancer of the membranes around internal organs, most often the lungs or abdomen of the patient. It is a deadly disease that comes from exposure to the mineral asbestos.

Asbestos was made into a popular insulator and component in building materials worldwide back in the 1930s because it was readily available, cost little, and its very resistant to fire and corrosion.  The use of Asbestos in the building materials has put hundreds of thousands of workers at risk for mesothelioma.

Many countries, including Denmark, began in the 1950s and 60s to reduce their use of Asbestos products after it was linked to mesothelioma cancer as well as other unhealthy conditions.Pleural Mesothelioma Asbestos Lung Cancer

In a Danish study, the research team used data from the years 1943 through 2009 about mesothelioma stored at the Danish Cancer Registry. The researchers discovered the total incidence of mesothelioma continued to rise throughout the study period showing a peak of 1.76 cases per 100,000 people during the years 2008-2009.

The study also identified more cases in the Region of Northern Jutland in comparison to Southern Denmark.  While mesothelioma survival rate has improved slightly, the researchers noted that the  prognosis for getting mesothelioma continues to remain poor based on a median rate of 12.5 months survival for men and 13.3 months survival for women in the years 2008 through 2009.

In the Danish Medical Journal, the authors conclude:

“The national malignant mesothelioma incidence for men continues to increase, perhaps showing a slight tendency towards deceleration in the most recent decade,”

But they go on to say that:

“A clear long-term effect of the Danish asbestos ban has not yet occurred.”

Lag Time between Asbestos Exposure and Mesothelioma Diagnosis

With mesothelioma, the lag time  (latency period) between exposure to asbestos  and the development of the disease can be many decades.   It is during the latency period that the disease is very difficult to detect and diagnose, much less tracing its source.  Frequently mesothelioma cancer is diagnosed late in its development, and it tends to progress quickly.  Estimates from the World Health Organization show that since 1994, more than 92,000 people have died from mesothelioma cancer.

RESULTS:

In Denmark, the national incidence of malignant mesothelioma cancer for men has been rising during the study period, reaching its total maximum of 1.76 in 2008-2009.  The incidence rate has remained relatively steady for women with a maximum of 0.5 in 1973 through 1977.

Northern Jutland and the surrounding region records the highest male incidence rate of mesothelioma since the late 1980s. The difference in relative risk for men in the Region of Southern Denmark and the Region of Northern Jutland was 1.53 during the period of 2008-2009.  The relative risk of developing mesothelioma cancer in the Region of Northern Jutland for the entire study period when collectively compared to the whole of Denmark was 1.38.  The study showed there are no notable regional differences for women at risk of developing mesothelioma.  Therefore, survival has slightly improved for both genders, but still remains poor with a median survival of 12.5 months for men and 13.3 months for women in the period of 2008 through 2009.

CONCLUSION:

Within Denmark the national malignant mesothelioma incidence for men continues to increase, perhaps showing a slight tendency towards deceleration in the most recent decade. A measurable long-term mitigating effect of the Danish ban on asbestos products  has not yet occurred.

The original Danish study appeared in the Danish Medical Journal. (Skammeritz, E, et al, “Regional difference in incidence of malignant mesothelioma in Denmark“, March 2013, Danish Medical Journal.

http://www.ncbi.nlm.nih.gov/pubmed/23484611

The Mesothelioma Research Foundation of America has brought readers the most important and ground-breaking news on the causes, diagnosis and treatment of mesothelioma. All Surviving Mesothelioma news is gathered and reported directly from the peer-reviewed medical literature. Written for patients and their loved ones, Surviving Mesothelioma news helps families make more informed decisions.

Related Mesothelioma Cancer Press Releases

New Cancer Treatments Using T-Cell Genetically Modified Therapy

Incredible results within some clinical trials are showing up for cancer treatments where genetically modify patients’ blood cells are created to target specific cancer disease.

Based on two clinical trials, nearly 90% of patients had their leukemia disappear after receiving an experimental therapy using genetically modified  CAR T-cells.   These trials were sponsored sponsored by Novartis AG NOVN.VX -0.72% of Switzerland and Seattle-based biotech Juno Therapeutics Inc.  The results were published in December and February of 2014.

Both trials included just a few patients: 22 children in the Novartis trial and 16 adults in the Juno trial.  All patients had a common childhood cancer, acute lymphoblastic leukemia, and these patients each had exhausted standard cancer treatments.

According to Dr. Daniel DeAngelo: “CAR T-cells are probably one of the most exciting concepts and fields to come out in cancer in a very, very long time.”  Dr. DeAngelo is a Boston-based hematologist and associate professor of medicine at Harvard Medical School.  He was is not involved in either of the clinical trials.

In an interview with The Wall Street Journal, Dr. Usman Azam said “I think that a cure for cancers such as leukemia and lymphoma through a CAR technology is plausible.  Oour job is to get this into patients as soon as we feasibly can.”

Dr. Azam is the leader of cell and gene therapies at Novartis, and also heads the new unit Novartis created partly to speed the therapies’ time to market.

T-Cell CAR therapies combine the methods of genetic tweaking and “immunotherapy,” which uses the patient’s immune system to fight disease. The genetic part of the method involves extracting disease-fighting white blood cells called T-cells from a patient’s blood. The T-cells are then genetically modified, grown in a laboratory dish for around a short period of time, and then injected back into the patient.

Genetically Modified T-Cell cancer therapy

The laboratory dish process is where T-cells are combined with a disabled virus.  The virus enables the T-cells to produce Chimeric Antigen Receptors (CARs) that can recognize and target malignant proteins on the surface of cancer cells.

Novartis is funding the development of their treatment in partnership with the University of Pennsylvania, while Juno’s funding is in partnership with teams at Memorial Sloan-Kettering Cancer Center in New York, Seattle Children’s Hospital and Seattle’s Fred Hutchinson Cancer Research Center.

For patients seeking potential solutions to their cancer, knowing who is developing new treatments brings them to the opportunity to participate in Clinical Trials to get early results to cancer cure.  Therefore, while Novartis and Juno are ahead in the race to bring Genetically Modified T-Cell cancer therapy to the mass of cancer patients, there is also others developing similar therapy methods including  Pfizer Inc., PFE -0.04% Kite Pharma Inc. KITE -3.75% and Celgene Corp. CELG -1.14%  (in collaboration with Bluebird Bio Inc. BLUE +1.43% ).

Genetically modified T-Cell therapy deploying CARs is very new;  so there are unresolved questions about the method of using this kind of therapy.

How Long Does T-Cell CAR Treatments Last Keeping Cancer In Remission?

Because the current clinical trials treated only a small number of patients, as well as many of those patients whose cancer went into remission after the T-Cell CAR treatment where then eligible for subsequent stem-cell transplants (which can also increase survival), there is no absolute evidence and history to yet determine the longevity this treatment produces.

Additionally, there is a potential dangerous side effect for some patients called “cytokine-release syndrome,” an immune response while the therapy is working, can cause a sharp drop in blood pressure and surge in the patient’s  heart rate.

In March 2014, a Juno-backed Sloan-Kettering trial was held over the deaths of two patients.  That has caused a temporary halt in the T-Cell CAR study because of worries about the dangerous immune response and two deaths.

But, the clinical trial is again recruiting patients giving those with very advanced leukemia fewer modified cells, and excluding those patients with a risk of heart failure.

Can T-Cell CAR Treatments Be Created At Affordable Cost?

Due to the genetic engineering involved with T-Cell CAR therapy which is very complex to manufacture with each laboratory batch being a unique personalized treatment customized to a cancer patient’s own blood cells, the inability to mass-produce T-Cell CAR therapy questions the implication about how much companies will charge for the therapy.

Dr. Malcolm Brenner, director of the Center for Cell and Gene Therapy at the Texas Children’s Hospital in Houston, reminds us that “What we’re talking about here is a single, very expensive therapy that’s used once for a specific patient and is not generalizable.”

While Citigroup believes T-Cell CAR therapy could cost in excess of $500,000 per patient, which it notes is roughly the same cost for a stem cell transplant, most analysts still think it is too soon to approximate the future revenue or price for this therapy.

Again, Dr. DeAngelo clarifies:  “This technology needs to be widely developed and accessible to patients; if the cost is going to be a hindrance, it’s going to be a really sad day.”

For these reasons and more,  Pfizer is taking a different approach to this treatment with a focus on managing scalability and cost.  “We would like to take it to the next level, where CAR therapies become a more standardized, highly controlled treatment,” said Mikael Dolsten, Pfizer’s head of global research and development.

Pfizer wants to develop a generic T-Cell CAR therapy for use in any patient, potentially lowering its cost.  So, Pfizer is collaborating with French biotech Cellectis SA, ALCLS.FR +1.89%  on T-Cell CAR research that is currently preclinical.

Even if  T-Cell CAR treatments being developed might justify “outrageous” prices, it is probably that health-care payers as well as patients might object and fight back.  International director of health-care research at Société Générale, Stephen McGarry, asks:  “When you look at the initial data with the Novartis therapy, you’re getting cures in some kids—what do you charge for that?”

So, the drug companies and biotechs must overcome big hurdles to get their T-Cell CAR therapies into hospitals, and manage their potential cost.  And the biggest challenge may be the cost of the therapies.

Mesothelioma Prognosis Stage One

Mesothelioma is a kind of cancer caused due to excessive exposure to asbestos. Its prognosis is dependent on the stage of the disease and the age of the patient. Apart from this, there is also the factor of health condition of the patient and the kind of mesothelioma.

Mesothelioma Prognosis

The prognosis and the life expectancy of the patient are dependent mainly on the stage of mesothelioma when it is diagnosed.  But with mesothelioma, unlike some other cancers, it is difficult to determine the developmental stage when the cancer is diagnosed. This is because the disease is quite rare and the initial symptoms are not easily diagnosable. As this deadly disease is diagnosed only at the advanced stage, the survival rate is not very high. The history of mesothelioma statistics indicate that 10% of the cases diagnosed for about 3 years and about 5% will live for about 5 years.  Still, if the disease is diagnosed early such as stage one and is treated effectively, then 50% will survive 2 years and 20% people will survive 5 years.

Mesothelioma Stage One

The Four Stages of Mesothelioma Cancer
Four Stages of Mesothelioma Cancer

Stage one mesothelioma indicates that the cancer is localized and has not spread to other parts of the body. It is found only in one area of the body like in the case of pleural mesothelioma, it is only in one part of the lung. There are different methods to identify the stage of mesothelioma for its prognosis:

Mesothelioma Stage One – Butchart Staging System

This method is considered to be oldest system to discover the degree of development for pleural mesothelioma. The staging is done based on the size of the primary tumor. In Stage One, only one of the sides of the lung has cancer which indicates that one part of the pleural membrane is affected by cancer. It could be also one side of the diaphragm and one lung.

Mesothelioma Stage One – The TNM Staging System

This is a recent kind of staging system which stage the cancer depending on the size of a tumor, presence of cancer in the lymph nodes and its spreading to other parts of the body.  When using the TNM method, stage one mesothelioma is found in the left or right pleura and has spread to either the lung, the pericardium or the diaphragm on the same side of the chest. In TNM stage one mesothelioma, the cancer is not found in lymph nodes and has not metastasized to other body parts.

When the Brigham System is used to stage malignant mesothelioma, the doctors generally focus and grade the stage of the cancer based on the successful removal of the primary tumor with surgery. So, with this approach and method the stage one mesothelioma patient has a better prognosis, because the other stages may not follow this stage indicating that the cancer has not spread to other parts of the body and has been restricted to only one part of the body. This method also provides for better treatment options.

However, it is quite difficult to diagnose this disease at stage one use both methods because the symptoms of mesothelioma are not clearly identifiable like they are in Stages Two, Three or Four.  In Stage One, the patient can be treated by undergoing a surgery to remove the primary tumor and the nearing tissue followed by radiation therapy or chemotherapy to kill any remaining cancer cells.

Please consider using our offer to ask oncologist and research leader, Dr. Parkash Gill, for a specific response to your mesothelioma question for FREE: Click Here to Ask Dr. Gill

More Mesothelioma Articles

CDC Data Shows Workers Exposed to Asbestos at risk of Mesothelioma Cancer

CDC - Center for Disease Control and Prevention
Government agency for disease control ( CDC )

 

Data released by the Centers for Disease Control and Prevention (CDC) has shown that despite federal restrictions on the commercial use of asbestos, workers who were exposed to asbestos-containing products on the job decades ago may still be at risk of being diagnosed with mesothelioma as well as other asbestos-related diseases. The Mesothelioma Research Foundation of America is recommending workers who were exposed to asbestos on the job and have developed symptoms akin to mesothelioma, lung cancer or other illnesses consider their options with medical treatment including participation in clinical trials of new drugs demonstrating the promise of cure for mesothelioma cancer.

History of Mesothelioma and Asbestos

Asbestos is a cancer-causing material that was commonly used for commercial, industrial and construction purposes before being restricted in the U.S. during the 1970s. However, because workers may take as many as 50 years after exposure to develop symptoms of an asbestos disease, many workers who worked with asbestos on the job are only now showing signs of mesothelioma, asbestosis, lung cancer or other related conditions.

Mesothelioma is the most deadly disease associated with asbestos exposure and is a type of cancer that affects the lining of the heart, lungs and abdomen.  Data collected and statistics compiled by the CDC demonstrate the  states with the highest number of mesothelioma deaths which include California, Florida, New York, Pennsylvania, Texas, New Jersey, Illinois and Washington. More than half of all mesothelioma deaths in the United States are recorded in these eight states.

Sources of Asbestos Exposure Causing Mesothelioma

Because of the wide variety of commercial applications for asbestos, workers across many industries may be at risk of developing an asbestos disease. Some of the job sites most commonly associated with asbestos-related cancers and other conditions include construction sites, oil refineries, power plants, shipyards, chemical plants, aluminum plants, metal works and steel mills.

Veterans of the U.S. Navy or Merchant Marines may also be at risk of developing mesothelioma or other asbestos-related diseases due to the asbestos products that were used on board ships. Workers at U.S. naval shipyards as well as private sector shipyards that were used by the Navy may also have been exposed to asbestos products or protective materials.

Conclusion

Individuals who were exposed to asbestos and have developed symptoms of mesothelioma, lung cancer, asbestosis or another asbestos-related disease should seek a  professional medical opinion.  The Mesothelioma Research Foundation of America (a not-for-profit research organization) provides free access to our mesothelioma research team for answers to your medical questions.  Simply Ask Dr. Gil.